Comment by Balgair

Whew, now that was a wikipedia binge. Thanks for the leaping off point! Unfortunately, our data is VERY noisy. We can do some techniques to smooth the data, but the unfortunate part is that the things that matter in biology are under the diffraction limit of light. Inherently, what we want out of the data will then be noisy. Gestalt structures are less noisy and these techniques can help with that (think using a fiber-optic read-out as you go into the brain for surgery so you know what region you are in), at least I think. Also, the 'elements' of our data set are unknown, but likely very large. Maybe in the 100s to 1000s, not 5 or 10. It turns out the brain is complicated, who knew?!

Still, thanks a ton for this info! I think it can really help with some computational bio stuff another lab is working on here (viral similarity in genes in your DNA)