Comment by dogma1138

Depends on what you define as the laws of physics.

We have cases where the laws of physics break for example singularties and it’s generally accepted that at certain energy levels forces can join or split for example during and shortly after the Big Bang the it’s assumed that all of the forces were joined together.

There is also the Higgs field which is not clear if it can change states or not and if it has done so at any period in the past which is not directly observable.

In fact the laws of physics “changing” is one of the possible answers to how the matter anti matter symmetry broke in the first place and allowed the universe as we know it to form.

However ofc any global change in any of the “fundamental” laws/constants will end all existence as we know it.