Comment by mrob

The lower resolution one looks worse, because when I see low-resolution art like that I expect to see pixel art, but it's just resampled high-resolution art. It doesn't exploit the non-point-sample reality of pixels to create the illusion of higher resolution like pixel art does.

The middle one changes the meaning of the green liquid next to the building. The original uses a bright saturated green, which is the standard visual code for "harmful to touch" (e.g. acid or radioactive waste). The modified version merely looks like dirty water. I haven't played the game so I don't know which is correct.