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Comment by wyxuan

5 years ago

Et voila: https://www.biorxiv.org/content/10.1101/2020.03.31.018556v1.... Also here's a source on the ventilator time: https://www.dropbox.com/s/8b2govfsa6n0xbq/NEJM_Clinical%20Ou...

I find it strange that this would be a new discovery, considering that even a casual search shows a decently large body of research specifically into the combinations of chloroquine and hydroxychloroquine with metformin.

"Confidential: Destroy when review is complete" A look behind the curtain.

  • Yep. Ding ding ding! Tried to post this link onto hn but it couldn't accept for some reason. This was a leaked paper submitted to NEJM.

Interesting but not sure how generalizable a study on genetically modified mice is. I threw HCQ and metformin into the Epocrates drug interaction checker and this is what I got back, "Monitor glucose: combo may incr. risk of hypoglycemia, including life-threatening (additive effects)"