Comment by meibo

Only if the server doesn't respond in time, that is - if you'd wanna prevent it from happening, you could just turn it off in the first place via GPO: https://docs.microsoft.com/en-us/windows/security/threat-pro...

I'd assume that's what most corporations do, since that's what it's there for.

I wouldn't 100% forsake the benefits of this stuff, since it does protect normal users - defender on modern Windows installs is good software and really does its job well, while staying out of your way most of the time. I'd leave it on for my parents.