Comment by heavyset_go

Photoshop works pretty well in Wine, and Windows runs quickly using KVM.

Linux also has native support for hardware pass-through if your machine has an IOMMU, so you can give virtual machines direct access to graphics cards and get GPU acceleration in your VM, along with USB devices, etc. VirtIO is built into the kernel and can provide you with paravirtualized network and storage access, which can speed things up considerably.