Comment by krunkcoin

"The CPU can't possibly get too cold" - Untrue. There are plenty of chips with what overclockers like to call "cold bugs".

Sequential logic (flipflops) has a setup time requirement. This means the combinatorial computation between any two connected pairs of flops (output of flop A to input of flop B) has to do its job fast enough such that the input of B stops toggling some amount of time before the next clock edge arrives at the flipflop. Violate that timing, and B will sometimes sample the wrong value, leading to an error.

Setup time is what most people are thinking about when they use LN2 or other exotic forms of cooling. By cooling things down, you usually improve the performance of combinatorial logic, which provides more setup time margin, allowing you to increase clock speed until setup time margin is small again.

But flops also have hold time requirements - their inputs have to remain stable for some amount of time after the clock edge, not just before. It's here where we can run into problems if the circuit is too cold. Imagine a path with relatively little combinatorial logic, and not much wire delay. If you make that path too fast, it might start violating hold time on the destination flop. Boom, shit doesn't work.