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Comment by photochemsyn

4 years ago

Acetaminophen is best avoided in my opinion. Long term liver damage is a major issue, particularly in conjunction with alcohol. There's also some evidence it's linked to cancer, and why take the risk? Ibuprofen (Advil) is probably much preferable in most cases, though definitely not for long-term chronic pain.

Long-term chronic pain is one condition where opiates actually make sense, although studies demonstrate that using cannabis + opiates allows the opiate dosage to be kept below the addiction threshold while providing equivalent relief.

> There's also some evidence it's linked to cancer

Isn’t everything? I would love to see a site that was more about the relative risks of cancer. Or even better, that queries us for our behaviours and then suggests where to spend our efforts to improve our quality of life, based on well supported research.

  • WARNING: Reading this comment is known to the State of California to cause cancer and birth defects or other reproductive harm.

    • We all have a risk of cancer per hour, so there is definitely a direct scientifically sound relationship between time spent reading your comment and the risk of cancer. It wouldn’t surprise me to find cancer risks associated with using specific devices (to read your comment). I presume there could be less likely psychological cause and effect: for example perhaps your comment causes anxiety and sleep deprivation with cancer as a side effect.

Acetaminophen doesn't cause long-term liver damage, it causes acute damage. The liver is very good at recovering from things as long as you don't poison it all at once.

It's actually ibuprofen that has the long-term risks, it will hurt your kidneys and stomach lining.