Comment by mattkrause

The normal adult dose is 300-600mg every 4-6 hrs, with a max dose of 3 (formerly 4) g/day. It's right on their webpage: https://www.tylenolprofessional.com/adult-dosage If you want something more formal, Medscape has pretty much the same numbers: https://reference.medscape.com/drug/tylenol-acetaminophen-34...

A one-off 1000mg is, as you say, fine but if you're maintaining at that level, you are literally right at the DNE limit.