Folding@home answers a related but different question. While AlphaFold returns the picture of a folded protein in its most energetically stable conformation, Folding@home returns a video of the protein undergoing folding, traversing its energy landscape.
Folding@home answers a related but different question. While AlphaFold returns the picture of a folded protein in its most energetically stable conformation, Folding@home returns a video of the protein undergoing folding, traversing its energy landscape.
It's not, but the question is (and has long been) whether the energy expended by folding@home is worth the scientific result. IMHO- probably not.
I would say no, the two approaches may be used to validate each other.
Good question… I’d imagine that other methods of folding solutions are still valuable, because AlphaFold needs to be checked.