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Comment by logicchains

1 year ago

I'm not saying metabolism doesn't vary among individuals, I'm saying for a given individual, their overall metabolism could decrease as they age due to having less muscle mass even if their rate per kg muscle didn't change.

What you say is true, but the main point of the paper is that they have measured a decrease of the metabolism after around 62 years even after correcting for the body composition, so the less muscle mass explains only a part of the decrease of the metabolism for older people.

The rest is likely to be due to slower rates of protein synthesis for the renewal of various body parts.