But yes[0], while metabolic pathways have been identified where artificial sweeteners certainly could cause insulin issues, RCT's have failed to find this effect expressed in vivo.
Artificial sweeteners do cause notable changes in gut biomes, and the effects of that are unknown.
Right, but for the purposes here, it's probably enough to say that several artificial sweeteners are unexpectedly bioactive. As such they perhaps are doing things that are undesirable.
I believe sucralose
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8880058/
lots to sort through though:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7014832/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7547772/
It's one of those truisms that has shotty science behind it.
*shoddy, not shotty.
But yes[0], while metabolic pathways have been identified where artificial sweeteners certainly could cause insulin issues, RCT's have failed to find this effect expressed in vivo.
Artificial sweeteners do cause notable changes in gut biomes, and the effects of that are unknown.
0: https://www.frontiersin.org/articles/10.3389/fnut.2020.59834...
Right, but for the purposes here, it's probably enough to say that several artificial sweeteners are unexpectedly bioactive. As such they perhaps are doing things that are undesirable.
Which artificial sweeteners?