Comment by bsder

Once you become a young adult, from that point on the total number of fat cells is conserved. Even liposuction will not change that.

This isn't completely hopeless, though. Fat cells "remember" the weight you are when they are created and fat cells turn over roughly 25% per year. However, it does mean that you need to hold your weight down for 3+ years for new fat cells to forget about the "fatter" you.