Comment by Podgajski
2 years ago
Nutritional studies are hard to get funding for in the first place, never mind the follow-ups.
They found nothing in the study, because IMI they were measuring the wrong neurotransmitters. Dopamine is not the cause of the symptoms. It has to do with glutamate and GABA Balance. Since stimulants can control effect glutamate and GABA as well as Dopamine , that’s why there is all the confusion.
B6 also plays a role in glutamate GABA balance through stimulating the glutamate dehydrogenase enzyme.
It looks like you have a whole stash of related papers. If you could send all those links, I'd really appreciate it.
They all stashed my brain after years of researching nutritional psychiatry.
As far as ADHD goes, I just suggest searching both PubMed and Google scholar for ADHD, glutamate and GABA.
I think glutamate and GABA play a larger, or fundenental role, in most psychiatric disorders.
May be a part of why so many people with psychiatric disorders (especially undiagnosed or untreated) often use nicotine and/or alcohol to cope. They both interact heavily with the GABAergic system. Alcohol also inhibits the activity of glutamate and reduces extracellular levels in certain brain regions. Too much glutamate in the brain can cause 'failure of different neurotransmission systems' and is neurotoxic.
It's too bad self-medicating with these substances comes with such awful downsides.
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