Comment by serguzest

I think this and many research efforts seem like how blind men are describing an elephant. They partially capture the truth. It seems to me B6 is just one of many cofactors that affect the one-carbon metabolism (methylation) besides epigenetics that play a role in ADHD. Recently I have been reading/watching materials from Bill Wash. His findings on ADHD make more sense to me. https://www.youtube.com/watch?v=PhdI6rqORv8 If you look up further online, I think you can find the biochemical rationale for these findings.