Comment by greenavocado

FD&C Red 40 (Allura Red AC): Linked to hyperactivity in children in some studies, although evidence is mixed. Theoretical concerns regarding disruption of cell membrane integrity, potentially leading to increased permeability and toxicity.

FD&C Yellow 5 (Tartrazine): Some in vitro studies suggest potential neurotoxic effects, though human evidence is lacking. Theoretical concerns regarding modulation of neurotransmitters, potentially leading to behavioral changes.

FD&C Yellow 6 (Sunset Yellow FCF): Similar to Yellow 5, some in vitro studies raise concerns, but human evidence is limited. Theoretical concerns regarding binding to DNA, potentially leading to mutagenic effects.

FD&C Blue 1 (Brilliant Blue FCF): Theoretical concerns regarding exacerbation of respiratory conditions like asthma. Theoretical concerns regarding increased cell membrane permeability, potentially leading to toxicity.

FD&C Blue 2 (Indigo Carmine): Limited human studies, but some animal research suggests potential neurological impacts. Theoretical concerns regarding triggering or exacerbating immunological reactions.

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