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Comment by timr

3 days ago

There is no such thing as proving something "safe". Go back and re-read the parent comment. The important point you are missing is that basically anything can be "linked" to cancer, and if you adopt the argument you are making, there would be nothing left.

Proving something safe is logically equivalent to proving that it is not unsafe, which is the same thing as proving a negative, which cannot be done. I cannot prove there is not a teapot circling Mars, and I cannot prove that even the most inert ingredient, at some dose, will not harm you.

Anyone who has lived in California knows this absurdity more intuitively than most people, because California's stupid laws adopt the logic you are proposing, and basically everything in daily life is labeled as cancer-causing.

A lot of folks in child comments are echoing your sentiment that something “cannot be proved safe”. Your argument that proving something is “not unsafe” is proving a negative is fallacious; the same can literally be said about anything (proving something is X is the same as proving it is not not-X). Proving drugs are safe and effective is literally one of the jobs of the FDA. If you do not believe that is possible, then we may as well tear down the entire drug regulatory apparatus. I imagine you and many other commenters will sing a different tune when posed with that suggestion.

So, let’s stop pretending it’s not possible. We require drug companies show their products are safe and efficacious, and there is both a scientific and a legal framework by which we do this. Let’s debate whether or not the same framework should be applied to food additives (I would argue it should) rather than claim it is not possible.

  • We require drug companies show their products are safe and efficacious, and there is both a scientific and a legal framework by which we do this.

    We don’t do this.

    What the FDA requires is acceptable safety in light of the benefit provided.

    The FDA approves highly toxic drugs all the time. Including ones with the risk of death. I don’t think anyone would call chemotherapy “safe”.

  • "Safe" for the FDA means the benefits outweigh the potential risks, not safe in absolute terms.

    If the FDA actually required every drug to be proven safe at any dose for everyone, we'd have no modern drugs.

> There is no such thing as proving something "safe".

Is that not what NCAP does?

Or what NTSB and FAA do with aviation?

You can prove that some things are safe. Does not mean infallible, means safe.

>There is no such thing as proving something "safe". Go back and re-read the parent comment. The important point you are missing is that basically anything can be "linked" to cancer, and if you adopt the argument you are making, there would be nothing left.

Really? You have some studies linking wheat and whole grains to cancer? And I don't mean wheat crops sprayed with glyphosate, just straight up wheat? Raspberries? Strawberries?

The reality is, very little of the actual natural food in our food chain is directly linked to cancer. All the additives we pile on top, on the other hand, are.

I would argue if we can't show a direct benefit to the consumer, it shouldn't be in the food chain. So, what is the direct benefit to a human consuming red-5? "It looks better on store shelves" isn't a direct benefit.

A shelf stabilizer? Sure, plenty of instances that makes a lot of sense. Food coloring that happens to be cheaper than natural alternatives? Just... no.

  • Yes, whole grains cause cancer if you make them into bread and toast the bread. The evidence is much stronger than for Red dye No. 3.

    https://www.fda.gov/food/process-contaminants-food/acrylamid...

    Strawberries are also linked to cancer, because they contain sugar.

    https://aacrjournals.org/cancerres/article/62/15/4339/508983...

    Almost all natural foods are linked to cancer. The important question is, how large is the risk?

    Dark toast is obviously much riskier than Red dye No. 3. We should think about that when we consider what to ban.

  • > The reality is, very little of the actual natural food in our food chain is directly linked to cancer.

    Natural things aren't inherently safer. Are alcohol and red meat both considered natural? Alcohol is a group 1 carcinogen (same as tobacco and asbestos) and red meat is group 2A (probably linked to cancer). A cursory search shows some studies linking fish consumption to cancer, though I have no idea how accurate those studies are.

    • Fun fact - some things that cause cancer can help prevent cancer. Several studies have concluded that marinading meat in beer significantly reduces the carcinogenic compounds developed by frying or grilling meat.

    • > Natural things aren't inherently safer.

      Yes they are.

      We have been exposed to, and made adjustments for, things in our environments.

      Novel chemicals have novel effects.

      There are plenty of dangerous natural things, and there are safe artificial things (I suppose).

      But there is a clear basis for eating food that your great grandparents would recognise.

      There is also a slowly mounting volume of evidence that there is something wrong with ultra processed foods, hard to say what, but it is becoming clear they are bad for us.

      So natural things are inherently safer, all else equal

      4 replies →

    • I’ll ignore for a second you completely avoided the point to move the goal posts.

      Alcohol isn’t a natural food, it’s a result of food rotting. Much like rotten meat, you can naturally assume negative side effects

      Red meat has positive benefits from its consumption, as does fish.

      What is the benefit of red5? If aren’t going to address that, I’ll assume you aren’t interested in anything but whataboutism and aren’t actually engaging in a good faith discussion.

      2 replies →