Comment by adrian_b

For more than a decade I have used only 4k displays (in most cases with 10 bit color components) on all my desktops and laptops, all of which run Linux.

I have never encountered any problem whatsoever. Only in Windows I have encountered sometimes scaling problems.

The only programs with which I had sometimes problems in Linux with high-DPI monitors have been commercial applications written in Java, some of which were very expensive. However those problems were not Linux-specific, but Java-specific, because those Java programs behaved equally bad on Windows.

For some reason, there seems to exist a high percentage of Java programmers who are incompetent at writing GUIs and the programs written by them neither follow the platform DPI settings nor allow the user to select a suitable display font, making their programs unusable without a magnifying glass when using high-DPI monitors. Moreover, I have encountered several expensive Java applications that crash and die immediately when used with monitors configured for 10-bit color instead of 8-bit color, both on Linux and on Windows.

So in more than a decade of using only high-DPI displays, I have never had problems with native Linux GUI applications, I have seldom encountered problems with native Windows applications and I have very frequently encountered problems with Java applications, regardless of the operating system on which they were run.