Comment by bluGill

Sort of. Without ATC you would still be safe - but airplanes would be much less common as no sane pilot will get anywhere close to other planes without someone in control to watch separations. That means instead of planes landing every 30 seconds they will be once every several minutes to make sure everyone takes turns - this isn't just about the runway, it is also the patterns around the airport, with many airplanes refusing to join the pattern because they are not sure they can fit in that close. Airports with more than one runway (which is nearly all commercial airports) will have issues trying to get patterns to work and so likely some runways won't even be used.

But if you do manage to get in the air you will be safe and get there. You would get used to long waits in hubs and 3 transfers to get there unless you live in a hub and are going to a hub. (Boston to Salt Lake city would be fly to NYC, then to Denver, then to Salt Lake. Even Boston to Atlanta would be a transfer in NYC). Those transfers would also involve long waits, right now airlines plane everyone to arrive at the hub and leave again more in about an hour and then little traffic for several hours. However after airlines will not coordinate schedules as they can't land so layovers will be several hours.