Comment by wrs

Once you pick one of the many “extended Markdowns” (one downside of MD is that there’s no agreement on what it actually is), they’re essentially equivalent.

But they’re not easily interchangeable, so what you’re really choosing is not the syntax you want to use, but the environment and ecosystem of tools you want to live in. For example, compare org-mode in Emacs (decades of plugins, open source, TUI-oriented, very nerdy) to Obsidian (Markdown, pretty good plugin selection, closed source, GUI-based, approachable).