Comment by GuB-42

Maybe there is that, but it can also just be an acquired test.

No one likes bitterness initially, the ability to taste bitterness is essentially a poison detector, but it may still trigger with substances that are safe, at least at the dosage you are taking them. As you age, you get to recognize these safe cases with your other senses and override your poison detector, which lets you appreciate the taste.

Herbal tea, tonic water, grapefruit juice, etc... All bitter, and most people dislike them initially, but after a while some will appreciate, and people don't drink them for the psychoactive effect.