Comment by bawana

Finasteride was discovered because of a tribe in south america with a high frequency of a mutant allele in the gene responsible for protein that converts T to DHT. They had no BPH. This led to the search for a competitive inhibitor of that enzyme.While under patent it was extremely lucrative to big pharma. The incentives of fame and greed will continue to plague our civilization as long as we embrace aggregating structures like corporations, advertising, social media, and instant worldwide communication to amplify human traits that were useful in small scale tribes.