Comment by robocat

  Advancing paternal age was not associated with an increase in risk for either Down syndrome or chromosomal disorders other than Down syndrome.

  Multiple neonatal and pediatric disorders have been linked to older paternal ages.  

  The risk of paternal age has been difficult to estimate and interpret because children often have parents whose ages are similar and likely to be confounded.

From "Disentangling the roles of maternal and paternal age on birth prevalence of Down syndrome and other chromosomal disorders using a Bayesian modeling approach" https://bmcmedresmethodol.biomedcentral.com/articles/10.1186...