Comment by trealira

I wouldn't say it's a non-issue. I've played 2D tile-based, pixel art games where the framerate dropped noticeably with too many sprites on screen, even though it felt like a 3DS should have been able to run it, and my computer isn't super low-end, either. You have more leeway, but it's possible to badly make optimized 2D games to the point where performance becomes an issue again.