Comment by shadowgovt

So it turns out the Philosopher's Stone is real, it just involves a 10,000-ton detection apparatus, a 17-mile-diameter accelerator tube as a source of prima, and a quark-gluon plasma.

Alchemists just had a skill issue.

(ETA: technically, so do the physicists if one wanted to actually get gold out of these interactions; the gold nuclei are coming out of the interactions with highly-random trajectories and just spalling into the collector or the downstream pipe, where the nuclei fall apart under the wild energies of a nearlight-velocity interaction. Can't use the gold if you can't slow it down to human-hands speed. Of course, at the energies and quantities we're talking about, it'd be cheaper to go into the asteroid belt, find a gold-heavy one, tow it to Earth, and dump it in a convenient ocean if you really want a bunch of gold).