Comment by krige

The Commodore Amigas had their 68k clock speed differ based on region due to carrier frequency difference (more specifically, 2x freq for NTSC, 1.6x for PAL, which resulted in almost the same, but not quite, clock speed).

It's interesting how the differing vertical resolutions between these two (200p /400i vs 256p /512i) also had some secondary effects on software design, it was always easy to tell if a game was made in NTSC regions or with global releases in mind because the bottom 20% of the screen was black in PAL.