Comment by tsoukase

Every degenerative CNS disease is caused by death of non replicating cells. By definition, the cure of such diseases is equivalent to immorality. This already highlights the importance and difficulty of such achievement.

The amyloid hypothesis seems too simple and superficial to account for a decades long process (it is speculated that Alzheimer's starts up to 20 years before symptom onset). The ultimate problem is to find the underlining cause(s) and not correlations.