Comment by fakedang

Because Iran is Shia and the rest of its neighbours are ruled by Sunnis. Some even have majority Shia populations that can be restive under a Sunni autocrat.

Even then, Iran still has strong ties with all of those neighbors. They trade actively, US sanctions be damned, and would pounce at the opportunity to invest in Iran if given the opportunity (Iran's industries are basically all owned by the Ayatollah and IRGC currently).