Comment by esseph
8 months ago
They might get a slight body high even on what would otherwise be considered heroic doses for their weight.
Things like lemon-tek to make the psilocybin more bioavailable were also not impactful to them, while being apparently extremely impactful for others.
It may be worth noting that antidepressant medication has a strong suppressing effect on psychedelics.
Depends on the type! Generally might be true for SSRIs but not always for TCAs or lithium which can have the opposite effect. https://pubmed.ncbi.nlm.nih.gov/8788508/ (just one example)
Well aware and accounted for.
If they’re doing high doses of psychedelics and only experiencing a body high, then they’re either on a drug blocking its effects, or they’re not taking a 5HT2-A agonist. They simply do not just produce a body high at high doses, you will know when you’re tripping.
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