Comment by golergka
8 months ago
In my experience, first times with drugs like MDMA are very important just because the tolerance builds up basically forever. First time with LSD however... Better safe than sorry. My first time wasn't that impressive, but it was safe and didn't involve any negative emotions. I've had many other times since, much more impressive and important.
Drugs' build up and tolerance varies wildly between the drugs, the person and the experience one seeks.
Chemically and physically, LSD for example is gone in a few days and certainly weeks. But taking two days in a row needs "insane" amounts to get you the same (physical, chemical) effect. MDMA is almost entirely gone in months, after which a normal dose will get the same (physical, chemical) effect. Good documentation with even calculators for this can be found online (be aware that it may not be allowed to even visit such sites in some countries!)
I deliberately emphasis the "physical and chemical" because the experience itself may be something you get used to. First time MDMA is wildly different from any time thereafter for many people. For many this is even stronger with LSD or Psilocybin. Many people report that the (first) experience opened up their mind and being profoundly and lasting. The more one gets used to the feeling the more this feeling itself becomes routine.
The intense love and euphoria from e.g. MDMA may be the same on an objective level, after letting the chemicals disappear over months, so technically one can achieve this level a few times a year. But the feeling itself is something one could get "used to" and "become bored by". Similar to how experiencing a rave sober for decades, or even how after decades of traveling it could get boring and a routine.
My point is: indeed first times are important. Even if the textbooks say that tolerance is gone after X time.