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Comment by epcoa

5 months ago

> and you can (and doubtless will) argue

Why so much aggression? I’ll accept those results as presented. I’ll concede a lot of the reviews are junk.

There’s also no argument against aggressive eradication efforts for HPV.

Though it does seem like in some parts of the world the incidence of truly HPV independent adenocarcinoma like GAS is substantially higher than global averages.

To the extent there's aggression it's because "But what about non-HPV cervical cancer?" has been a red herring for decades and I'm sick of that. 8% in particular demands some extraordinary evidence and I did not see any.

That GAS paper was entirely new to me. I am focused on the UK and to some extent Northern Europe because I live here and the pathologist I know who is intensely involved in this stuff works for whatever the mutual self-calibration panels are called in Northern Europe. So, while a Japanese woman's life is worth no less, my friend cares that a lab analysing a smear in Oslo gives consistent results with a lab doing that analysis in Manchester or Paris and Tokyo doesn't enter into it.

Demographically there are a lot of white women in these parts, which I'm sure skew the numbers, so I can well believe what you said in the last sentence. I'd still be sceptical it could be as high as 8% for real population groups.