Comment by Asooka

Because all the heavy number-crunching code is already written in C or Rust or as CUDA kernels, so the actual time spent running Python code is miniscule. If it starts to matter, I would probably reach for Cython first. PyPy is an extremely impressive project, but using it adds a lot of complexity to what is usually a glue language. It is a bit like writing a JIT for Bash.