Comment by namibj

There are no multi-statement queries in the binary protocol (where you get things like native cursors/pagination to efficiently iterate over result rows, and where you get the true parameter binding that is inherently robust against SQL injection.

It has a separate client to server packet that forces previous ones to complete as it will make otherwise-asynchronous (because pipelining) error reporting forcefully serial.

Other than this which is arguably not needed for queries that don't expect errors enough to need early/eager exception throwing during the course of a transaction, it's inherently naturally pipelined as you can just fire two or more statements worth of parameter binding and result fetching back-to-back without blocking on anything.