Comment by baobun

A lot of the world has moved on from virtualbox to primarily qemu+kvm and to some extent xen. Usually with some higher-level tool on top. Some of these are packages you can run on your existing OS and some are distributions with hypervisor for people who use VMs as part of their primary workflows. If you just want quick-and-easy one-off Windows VM and move on, check out quickemu.

Libvirt and virt-manager https://wiki.archlinux.org/title/Libvirt

Quickemu https://github.com/quickemu-project/quickemu

Proxmox VE https://www.proxmox.com/en/proxmox-ve

QubesOS https://qubes-os.org

Whonix https://whonix.org

XCP-ng https://xcp-ng.org/

You can also get some level of isolation by containers (lxc, docker, podman).