Comment by thaumasiotes
12 days ago
> stem-cell-based tooth replacement
Really? This sounds more like someone's plan to get grants to research stem cells than someone's plan to repair (or replace) teeth.
We already have a natural ability to grow new teeth that replace existing ones. Everybody does it... once. Where's the research into getting it to happen again?
Theet formation is a very early procces, even before the baby is born.
> Primary (baby) teeth start to form between the sixth and eighth week of prenatal development, and permanent teeth begin to form in the twentieth week.
So it's probably too late for you.
> So it's probably too late for you.
What's the argument here? You don't think I'm going to live for another 8 years?
Adult bones are probably harder, a growing unexpedted theet may be painful, I don't recomend to be the first to try the method.
Some people do have a third set of teeth in there.
Probably a genetic mutation, like the people that has 6 fingers in each hand.
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There has been a ton of research in the area of re-growing teeth from stem cells. A cursory search-engining will turn up a ton of articles, some going back decades, and many giving the impression that it's close to happening. I've been following it for awhile because I knew I'd be in the market for a new tooth eventually.
Here's an example of one from earlier this year at King's College, London: https://www.kcl.ac.uk/news/lab-grown-teeth-might-become-an-a...
There have been a lot of research around USAG-1, too [1]:
> Uterine sensitization-associated gene-1 (USAG-1) deficiency leads to enhanced bone morphogenetic protein (BMP) signaling, leading to supernumerary teeth formation.
[1] https://pubmed.ncbi.nlm.nih.gov/33579703/
If that could be targeted at a given tooth site (i.e. I don't want to go thru another round of deciduous teeth across my entire mouth) that would be pretty cool. We're each carrying a perfect growth matrix for new teeth, after all.
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