Comment by LorenPechtel
2 months ago
The age 45 bit isn't actually a guideline. Rather, finding naive but at risk individuals over 45 is quite difficult. They did not test it on anyone over 45, thus the FDA approval cuts off at 45.
2 months ago
The age 45 bit isn't actually a guideline. Rather, finding naive but at risk individuals over 45 is quite difficult. They did not test it on anyone over 45, thus the FDA approval cuts off at 45.
That’s definitely true, but if you look at the RCT data, there’s also a question of efficacy in older recipients.
For whatever reason the vaccine just doesn’t seem to work as well when administered to adults, even if they’re naive to the viruses.