Comment by trashb

Excel (or similar spreadsheet programs) is indeed great and has it's place. There are certain area's where there is no real replacement which is impressive. However I think that creating (interactive) applications is not one of the jobs Excel is the best tool for the job.

This exactly the argument I try to make Excel (spreadsheets) is a great interface for processing and working with certain type of data, think economic etc. but it is not great for other things. There we need a different interface to efficiently communicate our intent. For example programming languages or even writing a novel would not work very well in a Excel sheet (though no doubt someone has attempted it).