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Comment by tsimionescu

3 days ago

The guidelines haven't changed, but they should be. The association between cholesterol and CVD is specifically related to blood cholesterol levels. However, in healthy individuals, blood cholesterol levels are not strongly impacted by dietary cholesterol choices - since cholesterol is synthesized in the body, there is homeostasis, and higher cholesterol intake leads to lower rate of synthesis, maintaining the same blood levels.

However, some individuals suffer from a bad regulation of this homeostasis, and for them dietary cholesterol does lead to persistent high levels of blood cholesterol as well. So the guidelines should apply for them, but not for everyone else.