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Comment by isoprophlex

2 hours ago

10 mg a day, down from 20 but that made me feel wired, like I ate a bunch of 9V batteries for breakfast. Big pupils, trouble sleeping, manic thoughts, the works.

I'm a small, generally sensitive guy so ymmv...

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isoprophlex

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QuantumGood  1 hour ago

Thanks. Ever try Saffron extract standardized to crocin content (typically 2-3% crocin, dosed at 20-30 mg/day)?

One meta-analysis showed an antidepressant effect size around 1.2-1.6 , and unlike pharmaceutical antidepressants, saffron with standardized crocin has no well-documented or commonly reported withdrawal syndrome in clinical studies or reviews.