Comment by BenoitEssiambre

This matches my intuition. Systematic misalignment seems like it could be prevented by somewhat simple rules like the hippocratic oath or Asimov's Laws of robotics or rather probabilistic bayesian versions of these rules that take into account error bounds and risk.

The probabilistic version of "Do No Harm" is "Do not take excessive risk of harm".

This should work as AIs become smarter because intelligence implies becoming better bayesians which implies being great at calibrating confidence intervals of their interpretations and their reasoning and basically gaining a superhuman ability for evaluating the bounds of ambiguity and risk.

Now this doesn't mean that AIs won't be misaligned, only that it should be possible to align them. Not every AI maker will necessarily bother to align them properly, especially in adversarial, military applications.