Comment by singron

The crazy people depend a lot on routes, the part of the city, and the time of day. E.g. the 1 (Sacramento St/California St) is basically fine all the time. The 38 (Geary) and 14 (Mission) are OK during the commute rush since they are packed full of commuters, but outside of those times, you will eventually see all kinds of unsocial behavior (shouting, fights, defecation, etc.), especially closer to civic center/tenderloin/mission.