Comment by ndsipa_pomu

What a headache!

My practical view is to avoid spaces in directories and filenames, but to write scripts that handle them just fine (using BASH - I'm guilty of using it when more sane people would be using a proper language).

My ideological view is that unix/POSIX filenames are allowed to use any character except for NULL, so tools should respect that and handle files/dirs correctly.

I suppose for your usage, it'd be better to put the virtualenv directory into your path and then use #!/usr/bin/env python