Comment by lionkor

That seems highly unlikely. Let's assume that all compilers use the exact same padding in C structs, that all architectures use the same alignment, and that endianness is made up, that types are the same size across 64 and 32 bit platforms, and also pretend that pointers inside a struct will work fine when sent across the network; the question remains still: Why? Is THIS your bottleneck? Will a couple memcpy() operations that are likely no-op if your structs happen to line up kill your perf?