Comment by dugidugout

In the data science scenario you should just have proper tooling, for you it sounds like a REPL the agent can interface with. I do this with nREPL/CIDER; in Python-land a Jupyter kernel over MCP maybe. For stateful introspection where you don't control the tooling, tmux plus trivial glue gets you most of the way.

edit: There are much better solutions for Python-land below it seems :)