Comment by dnnddidiej
12 hours ago
And if you have one of those poisons the antedote is the other one.
Edit: only one way round! This is not medical advice. I am not a doctor. I am not your doctor or drinking doula.
12 hours ago
And if you have one of those poisons the antedote is the other one.
Edit: only one way round! This is not medical advice. I am not a doctor. I am not your doctor or drinking doula.
you suggest additional drinking methanol when you're "normally" drunk?? that's dangerously counterfactual.
No, ethanol is an antidote to methanol
Where's the authority on that?
Ethanol can be used as a temporary measure in methanol poisoning as it temporarily outcompetes methanol in the metabolic process. So it's only useful until proper medical help arrives when better alternatives such as fomepizole are administered. Even then there is no guarantee of success.
Methanol is still metabolized to dangerous formaldehyde and formic acid by the liver's alcohol dehydrogenase. The logic of giving ethanol or fomepizole is to slow down the rate of production methanol's dangerous metabolic byproducts so less damage is done, nevertheless those dangerous metabolites are still produced.
Ethanol's first-pass metabolite is acetaldehyde and it is still toxic but not to the same degree as those of methanol.
It is incorrect to say ethanol is an antidote for methanol poisoning. Using ethanol is a last-ditch stand to try and take some minor control of an otherwise out of control situation. There's nothing subtle about it—it's a blunderbuss approach that often doesn't work well because replacing one poison with a less toxic one is a pretty hit-and-miss process.
Antidotes counteract poisons, that's not what happens when you give ethanol in methanol poisonings.
vice versa
> Ethanol is the most commonly used antidote to block the metabolising of methanol. Ethanol works by competing with the metabolic breakdown of methanol, thereby preventing the accumulation of toxic byproducts.
MSF: https://methanolpoisoning.msf.org/en/for-health-professional...
I can see the ambiguity of my comment. I was trying to phrase as a riddle but can be interpreted both ways.
Same with antifreeze poisoning. If a kid drinks antifreeze, get him wasted to keep the liver busy.
ah got it. thanks for clarifying!