Comment by voxic11

No if you use GitHub Enterprise Cloud with data residency then you are on separate infrastructure. Here is the status page for the US enterprise cloud data residency https://us.githubstatus.com/posts/dashboard (which funny enough is reporting an issue atm).

You can tell if you are on the github enterprise with data residency because you will access github at a GHE.com domain rather than github.com. It definitely has better uptime than the public cloud but is not without its own issues.