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Comment by Aboutplants

9 days ago

First of all 5mg is a standard medical dosage for this medicine and isn’t likely to produce horrible experiences that you would get with much larger doses.

Second, you think it’s more ethical to let a patient suffer? Are you against emergency surgeries where a patient is unconscious after a car accident?

The dose in the paper is 5 grams, not mg

> Second, you think it’s more ethical to let a patient suffer? Are you against emergency surgeries where a patient is unconscious after a car accident?

My concern is that this induces more suffering. They are going to gain lucidity and then lose it again. That must be deeply distressing (for the family/relatives too). Can’t imagine that psychedelics help with the state of psychosis/hallucinations that advanced Alzheimer’s patients already experience too

  • From the Frontiers paper: "The patient received 5 g of orally administered psilocybin-containing mushrooms (Enigma strain". i.e., a standard dose of 5g of mushroom.

    • I’m assuming you’ve never taken mushrooms before (on average there is probably ~10mg psilocybin per dried gram, so 5g is 50mg which is on the high end of dosing, definitely not ‘standard’)

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