Comment by trio8453
7 hours ago
Not quite a "successful treatment":
> This case documents transient multidomain functional improvement in advanced Alzheimer’s disease following psilocybin administration. The findings do not imply disease reversal but suggest that residual functional capacity may persist in late-stage neurodegeneration and may become transiently accessible under specific neuromodulatory conditions.
Very interesting nonetheless.
> One month after the initial session, the patient remained continent and functionally improved compared with baseline. A second supervised psilocybin session using 3 g was subsequently performed and was associated with greater verbal expressivity, improved facial mimicry, spontaneous humor, emotionally valenced autobiographical imagery, and increased agility while walking.
> The patient spontaneously stated: “It is pleasant to come here.
This is just wonderful.
AFAIK psychedelics are thought to stimulate neurons into connecting with each other more than they normally do - both temporarily (which explains the short-term sensations) and also permanently (they stimulate neuroplasticity).
I'd love to see a before / after video of this or similar experiments, I'm really curious. I've seen similar ones for e.g. giving parkinsons' patients a dose of weed.