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Comment by Protostome

1 day ago

I will let the experts continue from here :) This review is from 2020, i bet things have progressed since then

https://pmc.ncbi.nlm.nih.gov/articles/PMC7169912/

3 comments

Protostome

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scotty79  1 day ago

It's not so much a mitochondrial transplant, as it is fertilized egg nucleus transplant. Not just mitochondria are used from the third donor but their whole egg (sans nucleus). So unless a human might develop from a bat egg just from swapping out nucleus, which I'm sure it's not the case, super-powered batman must remain a fantasy.

  • Protostome  1 day ago

    Oh, so that's what you were aiming for, LOL

    there are many reasons for this chimera not to be viable, mitochondria co-evolves with the nuclear DNA, you can't just take a mitochondria from a totally different species

    • scotty79  1 day ago

      Bats are kinda close though. Maybe it would require just a handfuls specific adjustments to nuclear DNA, at most. Worth a shot if it could give us for example 2x multiplier for a healthy lifespan. Even getting 10 year old mice would be very cool.