Comment by rictic
4 hours ago
The honest way to say this is that Fable is not useful for bio-related work. The author is working on processing RNA sequences and similar biology tasks, and Fable's classifier has a hair trigger on those tasks.
4 hours ago
The honest way to say this is that Fable is not useful for bio-related work. The author is working on processing RNA sequences and similar biology tasks, and Fable's classifier has a hair trigger on those tasks.
The author is working on an opensource C++ codebase and not on biology tasks. The work is around tooling.
It's like saying well a scalpel is used for medical reasons, sure. But manufacturing scalpels is metalworking, not medicine.
I think it's accurate to characterize the project as bio-related work: https://github.com/COMBINE-lab/salmon
> salmon is a wicked-fast program for highly-accurate, transcript-level quantification from RNA-seq data. It pairs a fast mapping stage — selective alignment, or alignment-free sketch mode (--sketch) — with a massively-parallel statistical model (EM/VBEM over equivalence classes) to estimate transcript abundances. You can give salmon raw sequencing reads, or regular alignments to the transcriptome (an unsorted BAM), and it uses the same inference engine either way.
Got it, so all those advances in medicine we were promised in exchange for higher electricity costs, global warming, and other pitfalls of AI were bunk?
It's also data that Anthropic likely scraped and included in their training data.
> The honest way to say this is that Fable is not useful for bio-related work.
It is way worse than that. Try "How does digestion work?" and you will see "Fable's safeguards flagged this message". It's a stupid rate of false positives.